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Methylsulfonylmethane, also known as MSM, occurs naturally in a variety of foods. Itís a sulfur containing organic compound with reputed pain relieving and disease prevention properties. MSM is a member of the DMSO family, which was widely used as an arthritis pain reliever some years ago and has a number of therapeutic uses.


Research into the nature and properties of MSM has yielded promising results. In a number of studies, MSM has been effective in relieving pain, reducing inflammation and may prevent the regrowth of tumors. Because of its anti-inflammatory and regenerative properties, MSM taken with glucosamine is often prescribed for patients recovering from joint replacement, or suffering from degenerative arthritis.


What MSM  Does:

Because MSM contains nearly 85% of the sulfur found in the human body, it is one of the main supports in the formation of healthy connective tissues. MSM provides the chemicals needed to form collagen, of which connective tissues are made. In addition, it is essential for healthy hair, nails and skin. The sulfur found in MSM activates and helps the body utilize a number of other important nutrients, including vitamins C, B1, B5 and biotin.


Health Benefits of MSM:

MSM is one of the active ingredients of DMSO, an organic compound with a long history of research to support its use in treating deterioration of the connective tissues, arthritis, skin conditions and some autoimmune disorders. Because MSM contains the ingredients the body uses to form skin and nails (elastin and collagen), it is an effective treatment for acne, psoriasis and other skin problems, and there is a great deal of anecdotal evidence to support its role in growing healthy hair and nails.


Degenerative Arthritis

MSM helps to stabilize the connective tissues found in cartilage, tendons and ligaments and also appears to have an anti-inflammatory action to reduce pain and swelling. (Dr. Sarah Brewer, MD)

MSM has been proven effective in tandem with glucosamine in rebuilding cartilage and other tissues that are damaged by degenerative arthritis. In addition, it offers pain relief and reduces inflammation which hampers healing.


Seasonal Allergic Rhinitis (Hay fever)

In one study, patients taking MSM supplements reported relief from hay fever symptoms. Those taking a placebo showed no improvement. The dosage in the study was 2600 mg daily, and duration of treatment was six weeks.


Prevents Autoimmune diseases

Two animal-based studies using animals that were genetically susceptible to autoimmune disease suggest that MSM may play a role in preventing the development of immune system disorders. Scientists suggest research using humans subjects to confirm this promising use of MSM.


Prevents Onset of Colon and Breast Cancer

Separate research studies using animals suggest strongly that MSM may help prevent the formation of tumors and cancerous cells.


Possible Side Effects of MSM

A 30-day study of MSM supplementation at a dosage of 2600 mg per day revealed no adverse side effects. The adverse effects of long term supplementation with MSM has not been studied, but there are no reports of adverse side effects of MSM in popular or anecdotal literature.



MSM is effective in treating the pain and swelling associated with degenerative arthritis and other disorders of the connective tissues. When taken in tandem with glucosamine, MSM can actually help repair and restore the damage done to the ligaments, bones and cartilage. It has also been proven effective in the treatment of interstitial cystitis, and can reduce the severity of hay fever.


Besides the clinically supported claims for MSM, thereís a large body of anecdotal and testimonial evidence to support the use of MSM supplements for treatment of headache, eczema, acne, thinning hair, unhealthy nails and skin, colon cancer, and sports injuries.


In the absence of long term side effects, doctors often recommend glucosamine with MSM for treatment of joint and arthritis pain.


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